Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9840512 | 1.00 | RARB (0.58) | RARBSMN1; SMN2MAPTRAB9AGAA | |
| SCHEMBL9839577 | 1.00 | RARB (0.58) | RARBSMN1; SMN2MAPTRAB9AGAA | |
| SCHEMBL9839806 | 1.00 | RARB (0.58) | RARBSMN1; SMN2MAPTRAB9AGAA | |
| SCHEMBL9840291 | 0.99 | RARB (0.56) | RARBSMN1; SMN2MAPTRAB9AGAA | |
| SCHEMBL9839540 | 0.95 | RARB (0.60) | RARBSMN1; SMN2MAPTRAB9AGAA | |
| SCHEMBL9840801 | 0.95 | RARB (0.60) | RARBSMN1; SMN2MAPTRAB9AGAA | |
| SCHEMBL9840561 | 0.95 | RARB (0.51) | RARBSMN1; SMN2MAPTRAB9AGAA | |
| SCHEMBL9840634 | 0.95 | RARB (0.60) | RARBSMN1; SMN2MAPTRAB9AGAA | |
| SCHEMBL9840775 | 0.95 | RARB (0.60) | RARBSMN1; SMN2MAPTRAB9AGAA | |
| SCHEMBL9840788 | 0.94 | RARB (0.58) | RARBSMN1; SMN2MAPTRAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220297-B1 | NITROGEN-CONTAINING HETEROCYCLES | MERCK PATENT GmbH (DE) | 1991-12-11 | — | — | EP | disclosed |