Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.33 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15809387 | 0.84 | TSHR (0.41) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL4145527 | 0.82 | TSHR (0.42) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL10585232 | 0.81 | CES1 (0.30) | CES1 | |
| SCHEMBL28353804 | 0.80 | TSHR (0.43) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL2469279 | 0.79 | TSHR (0.30) | TSHR | |
| SCHEMBL16353761 | 0.78 | CES1 (0.47) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL7118800 | 0.77 | TSHR (0.47) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL9637020 | 0.77 | TSHR (0.56) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL7591304 | 0.76 | CES1 (0.48) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL7753980 | 0.76 | HSD17B10 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992559-A | Electrochromic displays, antistatic agents, pH detectors, electrodes | COOKSON GROUP PLC (GB) | 1991-02-12 | — | — | US | disclosed |
| EP-0303360-A1 | Electroconductive polymers | COOKSON GROUP plc (GB) | 1989-02-15 | — | — | EP | disclosed |
| EP-0253594-A2 | Polymerisable thiophene monomers, their production and polymers prepared therefrom | COOKSON GROUP plc (GB) | 1988-01-20 | — | — | EP | disclosed |