Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 8/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9840494 | 0.99 | RARB (0.59) | RARBSMN1; SMN2MAPTRAB9AKDM4E | |
| SCHEMBL9839752 | 0.99 | RARB (0.59) | RARBSMN1; SMN2MAPTRAB9AKDM4E | |
| SCHEMBL9840675 | 0.99 | RARB (0.59) | RARBSMN1; SMN2MAPTRAB9AKDM4E | |
| SCHEMBL9840863 | 0.99 | RARB (0.59) | RARBSMN1; SMN2MAPTRAB9AKDM4E | |
| SCHEMBL10719851 | 0.99 | RARB (0.56) | RARBSMN1; SMN2MAPTRAB9AKDM4E | |
| SCHEMBL9840511 | 0.96 | RARB (0.52) | RARBSMN1; SMN2MAPTRAB9AKDM4E | |
| SCHEMBL9786474 | 0.94 | RARB (0.59) | RARBSMN1; SMN2MAPTRAB9AKDM4E | |
| SCHEMBL10702381 | 0.93 | RARB (0.58) | RARBSMN1; SMN2MAPTRAB9AKDM4E | |
| SCHEMBL9819195 | 0.93 | RARB (0.58) | RARBSMN1; SMN2MAPTRAB9AKDM4E | |
| SCHEMBL7094247 | 0.93 | RARB (0.58) | RARBSMN1; SMN2MAPTRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220297-B1 | NITROGEN-CONTAINING HETEROCYCLES | MERCK PATENT GmbH (DE) | 1991-12-11 | — | — | EP | disclosed |