Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | HTT | P42858 | 5/20 | 0.41 |
| ▸ | HBB | P68871 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SLC25A5 | P05141 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27536345 | 0.81 | MAPT (0.43) | MAPTHTTHBBALOX15SLC25A5 | |
| SCHEMBL10513601 | 0.81 | MAPT (0.43) | MAPTHTTHBBALOX15SLC25A5 | |
| SCHEMBL14515537 | 0.78 | SMN1; SMN2 (0.33) | MAPTHTTALDH1A1MEN1KMT2A | |
| SCHEMBL28302614 | 0.78 | MAPT (0.43) | MAPTHTTHBBALOX15SLC25A5 | |
| SCHEMBL28301099 | 0.78 | MAPT (0.43) | MAPTHTTHBBALOX15SLC25A5 | |
| SCHEMBL27674572 | 0.78 | MAPT (0.43) | MAPTHTTHBBALOX15SLC25A5 | |
| SCHEMBL27332488 | 0.78 | MAPT (0.43) | MAPTHTTHBBALOX15SLC25A5 | |
| SCHEMBL27396758 | 0.77 | MAPT (0.48) | MAPTHTTALDH1A1MEN1KMT2A | |
| SCHEMBL6280801 | 0.76 | MAPT (0.42) | MAPTHTTHBBALOX15SLC25A5 | |
| Hydrochloric Acid SCHEMBL27475583 | 0.76 | MAPT (0.42) | MAPTHTTHBBALOX15SLC25A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019570-A | Antibioics | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-05-28 | — | — | US | disclosed |