Fluoride

Fluoride

SCHEMBL9841745

CCC1CCC(Sc2ccccc2)CC1.F.F.F.F.F

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 1/20 0.46
PRMT6 Q96LA8 1/20 0.46
ALDH1A1 P00352 2/20 0.33
DDB1 Q16531 1/20 0.33
CRBN Q96SW2 1/20 0.33
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
ALOX12 P18054 1/20 0.33
DRD4 P21917 1/20 0.33
MAOA P21397 2/20 0.33
MAOB P27338 2/20 0.33
F2 P00734 2/20 0.32
PRSS1 P07477 2/20 0.32
POLB P06746 1/20 0.32
GRIN2B Q13224 3/20 0.31
GRIN1 Q05586 2/20 0.31
MAPK1 P28482 1/20 0.31
LMNA P02545 1/20 0.31
SIGMAR1 Q99720 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL9841703 0.95 CARM1 (0.43) CARM1PRMT6ALDH1A1DDB1CRBN
Fluoride SCHEMBL9841325 0.83 CARM1 (0.42) CARM1PRMT6GAAMAPTDRD4
Fluoride SCHEMBL9841806 0.82 CARM1 (0.41) CARM1PRMT6ALDH1A1GAAMAPT
SCHEMBL102816 0.82 CARM1 (0.50) CARM1PRMT6ALDH1A1DDB1CRBN
SCHEMBL12110641 0.82 CARM1 (0.50) CARM1PRMT6ALDH1A1DDB1CRBN
Fluoride SCHEMBL9842093 0.82 CARM1 (0.41) CARM1PRMT6GAAMAPTDRD4
Fluoride SCHEMBL9842012 0.80 CARM1 (0.40) CARM1PRMT6GAAMAPTDRD4
Fluoride SCHEMBL9841535 0.80 CARM1 (0.40) CARM1PRMT6GAAMAPTDRD4
Fluoride SCHEMBL9842030 0.80 CARM1 (0.40) CARM1PRMT6GAAMAPTDRD4
Diphenylsulfane SCHEMBL7414466 0.80 SMN1; SMN2 (0.40) ALDH1A1KDM4EGAAMAPTALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5055223-A For use in liquid crystal display elements MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-10-08 US disclosed