Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | LSS | P48449 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9841211 | 1.00 | HTT (0.40) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL9842010 | 1.00 | HTT (0.40) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL9841425 | 0.99 | HTT (0.40) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL9841725 | 0.97 | HTT (0.42) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL9841176 | 0.97 | HTT (0.42) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL9841740 | 0.97 | HTT (0.42) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL9841607 | 0.95 | KMT2A (0.41) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL9841520 | 0.95 | HTT (0.43) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL9841751 | 0.92 | KMT2A (0.44) | HTTKMT2ASMN1; SMN2TDP1F2 | |
| SCHEMBL9841311 | 0.91 | HTT (0.43) | HTTKMT2ASMN1; SMN2TDP1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055223-A | For use in liquid crystal display elements | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-10-08 | — | — | US | disclosed |