Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 12/20 | 0.44 |
| ▸ | CA9 | Q16790 | 12/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2600399 | 0.77 | CHRM3 (0.44) | CA12CA9CHRM3LMNACHRM2 | |
| SCHEMBL2600393 | 0.73 | CHRM3 (0.42) | CA12CA9CHRM3LMNACHRM2 | |
| SCHEMBL14123288 | 0.71 | CHRM3 (0.49) | CA12CA9CHRM3LMNACHRM2 | |
| SCHEMBL14568528 | 0.71 | CA12 (0.43) | CA12CA9CHRM3LMNACHRM2 | |
| SCHEMBL14256083 | 0.68 | CHRM3 (0.45) | CA12CA9CHRM3LMNACHRM2 | |
| SCHEMBL29102058 | 0.67 | CA12 (0.47) | CA12CA9CA2TSHRHSD17B10 | |
| SCHEMBL12723468 | 0.67 | CA12 (0.47) | CA12CA9CHRM3LMNACHRM2 | |
| SCHEMBL31333069 | 0.67 | CHRM3 (0.40) | CA12CA9CHRM3LMNACHRM2 | |
| SCHEMBL5798986 | 0.66 | — | — | |
| SCHEMBL5600204 | 0.64 | CA12 (0.59) | CA12CA9CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041516-A | Macromolecules | CORNELL RESEARCH FOUNDATION, INC. (US) | 1991-08-20 | — | — | US | disclosed |