Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | DHFR | P00374 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CAMKK2 | Q96RR4 | 12/20 | 0.42 |
| ▸ | CAMKK1 | Q8N5S9 | 10/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842453 | 0.91 | TTR (0.48) | TTRKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL9842807 | 0.89 | TTR (0.46) | TTRKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL9842727 | 0.88 | TTR (0.46) | TTRKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL9842652 | 0.87 | TTR (0.45) | TTRKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL9842361 | 0.85 | RARB (0.38) | TTRKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL9842489 | 0.84 | TTR (0.46) | TTRKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL5837226 | 0.83 | PTGDR2 (0.40) | CAMKK2CAMKK1 | |
| SCHEMBL5836884 | 0.83 | PTGDR2 (0.40) | CAMKK2CAMKK1 | |
| SCHEMBL9842723 | 0.82 | TTR (0.44) | TTRKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL9842253 | 0.81 | KDM4E (0.43) | TTRKDM4EMEN1USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413785-A1 | LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS. | MERCK PATENT GMBH (DE) | 1991-02-27 | — | — | EP | disclosed |
| WO-1990009420-A1 | LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-23 | — | — | WO | disclosed |