Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 13/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 13/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 9/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 9/20 | 0.50 |
| ▸ | CNR1 | P21554 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9630128 | 0.86 | CNR2 (0.63) | CNR2HDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL9585436 | 0.81 | CNR2 (0.57) | CNR2CNR1GAA | |
| SCHEMBL3180782 | 0.81 | CNR2 (0.60) | CNR2CNR1GAA | |
| SCHEMBL1927472 | 0.80 | CNR2 (0.64) | CNR2CNR1GAA | |
| SCHEMBL5097779 | 0.80 | CNR2 (0.67) | CNR2CNR1 | |
| Hydrochloric Acid SCHEMBL1928223 | 0.79 | CNR2 (0.63) | CNR2CNR1GAA | |
| SCHEMBL1927566 | 0.79 | CNR2 (0.59) | CNR2CNR1GAA | |
| SCHEMBL1925621 | 0.78 | CNR2 (0.62) | CNR2CNR1GAA | |
| SCHEMBL2342868 | 0.78 | CNR2 (0.62) | CNR2CNR1GAA | |
| SCHEMBL1929381 | 0.78 | CNR2 (0.72) | CNR2CNR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432740-A2 | 2-Substituted 4-(3-alkyl-5-tert.-butyl-4-hydroxy-phenyl)-thiazole, process for their preparation, medicaments containing them and their utilization | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-06-19 | — | — | EP | disclosed |