Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 5/20 | 0.57 |
| ▸ | RARB | P10826 | 4/20 | 0.53 |
| ▸ | RARA | P10276 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842584 | 1.00 | PTPN11 (0.57) | PTPN11RARBRARATP53TSHR | |
| SCHEMBL9842401 | 0.99 | PTPN11 (0.55) | PTPN11RARBRARATP53TSHR | |
| SCHEMBL9842537 | 0.92 | RARB (0.48) | PTPN11RARBRARAMCL1 | |
| SCHEMBL9406249 | 0.87 | PTPN11 (0.62) | PTPN11RARBRARATP53TSHR | |
| SCHEMBL9723193 | 0.86 | PTPN11 (0.60) | PTPN11RARBRARATP53TSHR | |
| SCHEMBL10398215 | 0.84 | PTPN11 (0.53) | PTPN11RARBRARATP53TSHR | |
| SCHEMBL9842454 | 0.84 | RARB (0.60) | RARBRARA | |
| SCHEMBL9842700 | 0.84 | RARB (0.60) | RARBRARA | |
| SCHEMBL9842548 | 0.84 | RARB (0.60) | RARBRARA | |
| SCHEMBL10398260 | 0.83 | PTPN11 (0.52) | PTPN11RARBRARATP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413785-A1 | LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS. | MERCK PATENT GMBH (DE) | 1991-02-27 | — | — | EP | disclosed |
| WO-1990009420-A1 | LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-23 | — | — | WO | disclosed |