Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 5/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | RORA | P35398 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842649 | 1.00 | RARB (0.40) | RARBFAAHRORCRORANR1H4 | |
| SCHEMBL9842792 | 1.00 | RARB (0.40) | RARBFAAHRORCRORANR1H4 | |
| SCHEMBL9842608 | 1.00 | RARB (0.40) | RARBFAAHRORCRORANR1H4 | |
| SCHEMBL9842479 | 1.00 | RARB (0.40) | RARBFAAHRORCRORANR1H4 | |
| SCHEMBL9842603 | 0.99 | RARB (0.39) | RARBFAAHRORCRORANR1H4 | |
| SCHEMBL9842698 | 0.96 | TP53 (0.40) | RARBTP53POLBMAPTS1PR1 | |
| SCHEMBL11102482 | 0.88 | KMT2A (0.42) | RARBFAAHTP53POLBMAPT | |
| SCHEMBL11102162 | 0.88 | KMT2A (0.42) | RARBFAAHTP53POLBMAPT | |
| SCHEMBL11102159 | 0.88 | KMT2A (0.42) | RARBFAAHTP53POLBMAPT | |
| SCHEMBL11102477 | 0.88 | KMT2A (0.42) | RARBFAAHTP53POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413785-A1 | LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS. | MERCK PATENT GMBH (DE) | 1991-02-27 | — | — | EP | disclosed |
| WO-1990009420-A1 | LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-23 | — | — | WO | disclosed |