Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CFD | P00746 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728506 | 1.00 | MAPT (0.40) | MAPTRECQLKMT2AKDM4EMEN1 | |
| SCHEMBL8747106 | 0.89 | MAPT (0.36) | MAPTRECQLKMT2AKDM4EMEN1 | |
| SCHEMBL8198326 | 0.86 | MAPT (0.42) | MAPTRECQLKMT2AKDM4EMEN1 | |
| SCHEMBL13508311 | 0.83 | RECQL (0.40) | MAPTRECQLKMT2AKDM4EMEN1 | |
| Clothianidine SCHEMBL19386022 | 0.82 | RECQL (0.39) | MAPTRECQLKMT2AKDM4EMEN1 | |
| Clothianidine SCHEMBL2413061 | 0.81 | RECQL (0.39) | MAPTRECQLKMT2AKDM4EMEN1 | |
| SCHEMBL4655363 | 0.81 | RECQL (0.44) | MAPTRECQLKMT2AKDM4EMEN1 | |
| SCHEMBL4655361 | 0.81 | RECQL (0.44) | MAPTRECQLKMT2AKDM4EMEN1 | |
| Clothianidine SCHEMBL21214 | 0.81 | RECQL (0.39) | MAPTRECQLKMT2AKDM4EMEN1 | |
| Clothianidine SCHEMBL237824 | 0.81 | RECQL (0.39) | MAPTRECQLKMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418199-A2 | Guanidine derivatives | CIBA-GEIGY AG (CH) | 1991-03-20 | — | — | EP | claimed |
| EP-0418199-A2 | Guanidine derivatives | CIBA-GEIGY AG (CH) | 1991-03-20 | — | — | EP | disclosed |