Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Juarezic Acid SCHEMBL9843114 | 0.95 | TSHR (0.62) | TSHRTDP1ALDH1A1CYP3A4CA2 | |
| Styrene SCHEMBL9311792 | 0.88 | TSHR (0.66) | TSHRTDP1ALDH1A1CYP3A4CA2 | |
| SCHEMBL8656081 | 0.87 | TSHR (0.74) | TSHRTDP1ALDH1A1CYP3A4CA2 | |
| SCHEMBL31270696 | 0.84 | TDP1 (0.64) | TSHRTDP1ALDH1A1CYP3A4CA2 | |
| Styrene SCHEMBL491218 | 0.83 | TSHR (0.72) | TSHRTDP1ALDH1A1CYP3A4CA2 | |
| Styrene SCHEMBL9718415 | 0.82 | TSHR (0.55) | TSHRTDP1ALDH1A1CYP3A4CA2 | |
| SCHEMBL5924740 | 0.80 | TSHR (0.67) | TSHRTDP1ALDH1A1CYP3A4CA2 | |
| Styrene SCHEMBL1092186 | 0.79 | TSHR (0.66) | TSHRTDP1ALDH1A1CYP3A4CA2 | |
| Juarezic Acid SCHEMBL1627203 | 0.79 | TSHR (0.55) | TSHRTDP1CYP3A4ACHEATM | |
| Juarezic Acid SCHEMBL8887961 | 0.79 | TSHR (0.55) | TSHRTDP1CYP3A4ACHEATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410483-A1 | Developer for developing electrostatic images and image forming apparatus | CANON KABUSHIKI KAISHA (JP) | 1991-01-30 | — | — | EP | disclosed |