SCHEMBL9843779

SCHEMBL9843779

CC1O[C@@](Cn2cncn2)(c2ccc(Cl)cc2)C1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 7/20 0.44
THRB P10828 1/20 0.44
KDM4E B2RXH2 2/20 0.41
HTT P42858 2/20 0.41
POLB P06746 1/20 0.41
HSP90AA1 P07900 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
CYP2C9 P11712 3/20 0.40
CYP1A2 P05177 2/20 0.40
CYP2D6 P10635 2/20 0.40
CYP2C19 P33261 2/20 0.40
KMT2A Q03164 3/20 0.39
ALDH1A1 P00352 2/20 0.39
HPGD P15428 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MEN1 O00255 1/20 0.39
GAA P10253 1/20 0.36
HSD17B10 Q99714 1/20 0.36
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9199001 1.00 CYP3A4 (0.44) CYP3A4THRBKDM4EHTTPOLB
SCHEMBL9736709 1.00 CYP3A4 (0.44) CYP3A4THRBKDM4EHTTPOLB
SCHEMBL9735464 1.00 CYP3A4 (0.44) CYP3A4THRBKDM4EHTTPOLB
SCHEMBL9741267 1.00 CYP3A4 (0.44) CYP3A4THRBKDM4EHTTPOLB
SCHEMBL9198999 1.00 CYP3A4 (0.44) CYP3A4THRBKDM4EHTTPOLB
SCHEMBL9199815 1.00 CYP3A4 (0.44) CYP3A4THRBKDM4EHTTPOLB
Oxalic Acid SCHEMBL9201711 0.93 CYP3A4 (0.40) CYP3A4THRBKDM4EHTTPOLB
Oxalic Acid SCHEMBL9201703 0.93 CYP3A4 (0.40) CYP3A4THRBKDM4EHTTPOLB
Nitric Acid SCHEMBL9202704 0.91 KDM4E (0.47) CYP3A4THRBKDM4EHTTPOLB
Nitric Acid SCHEMBL9202699 0.91 KDM4E (0.47) CYP3A4THRBKDM4EHTTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0431968-A1 Oxetane derivatives, their preparation and their use as anti-fungal or fungicidal agents Sankyo Company Limited (JP) 1991-06-12 EP disclosed