Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 3/20 | 0.54 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.54 |
| ▸ | CASP2 | P42575 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 3/20 | 0.50 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.49 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21204364 | 0.88 | LPAR1 (0.55) | LPAR1LPAR2ENPP2CASP2FAAH | |
| SCHEMBL21204352 | 0.88 | LPAR1 (0.55) | LPAR1LPAR2ENPP2CASP2FAAH | |
| SCHEMBL16639380 | 0.88 | LPAR1 (0.55) | LPAR1LPAR2ENPP2CASP2FAAH | |
| SCHEMBL21204263 | 0.88 | LPAR1 (0.55) | LPAR1LPAR2ENPP2CASP2FAAH | |
| SCHEMBL21204365 | 0.86 | LPAR1 (0.54) | LPAR1LPAR2ENPP2CASP2FAAH | |
| SCHEMBL21204356 | 0.86 | LPAR1 (0.54) | LPAR1LPAR2ENPP2CASP2FAAH | |
| SCHEMBL17056238 | 0.86 | LPAR1 (0.71) | LPAR1LPAR2ENPP2CASP2FAAH | |
| SCHEMBL16640031 | 0.86 | LPAR1 (0.71) | LPAR1LPAR2ENPP2CASP2FAAH | |
| SCHEMBL13034204 | 0.85 | LPAR1 (0.58) | LPAR1LPAR2ENPP2CASP2FAAH | |
| SCHEMBL13034203 | 0.85 | LPAR1 (0.58) | LPAR1LPAR2ENPP2CASP2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410659-A2 | Method and composition to impart improved conditioning properties to the hair | HELENE CURTIS, INC. (US) | 1991-01-30 | — | — | EP | disclosed |