Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 6/20 | 0.67 |
| ▸ | DRD3 | P35462 | 5/20 | 0.67 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.67 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.67 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.67 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.67 |
| ▸ | DRD1 | P21728 | 3/20 | 0.67 |
| ▸ | HTR2A | P28223 | 3/20 | 0.67 |
| ▸ | HTR2C | P28335 | 3/20 | 0.67 |
| ▸ | HTR3A | P46098 | 3/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.67 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.67 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.67 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.67 |
| ▸ | HTR6 | P50406 | 2/20 | 0.67 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.67 |
| ▸ | CNR1 | P21554 | 2/20 | 0.67 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844215 | 0.89 | HRH1 (0.67) | HRH1DRD3HRH4LMNACHRM2 | |
| SCHEMBL9844340 | 0.86 | DRD3 (0.72) | HRH1DRD3HRH4LMNACHRM2 | |
| Hydrochloric Acid SCHEMBL9844514 | 0.85 | DRD3 (0.71) | HRH1DRD3HRH4LMNACHRM2 | |
| SCHEMBL9844519 | 0.84 | DRD3 (0.72) | HRH1DRD3HRH4LMNACHRM2 | |
| SCHEMBL9844280 | 0.83 | DRD3 (0.68) | HRH1DRD3HRH4LMNACHRM2 | |
| Hydrochloric Acid SCHEMBL9844266 | 0.83 | DRD3 (0.70) | HRH1DRD3HRH4LMNACHRM2 | |
| Hydrochloric Acid SCHEMBL9791328 | 0.83 | DRD3 (0.67) | HRH1DRD3HRH4LMNACHRM2 | |
| SCHEMBL9844413 | 0.83 | DRD3 (0.69) | HRH1DRD3HRH4LMNACHRM2 | |
| SCHEMBL9844348 | 0.82 | DRD3 (0.75) | HRH1DRD3HRH4LMNACHRM2 | |
| SCHEMBL9844494 | 0.82 | DRD3 (0.66) | HRH1DRD3HRH4LMNACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451772-A1 | Piperidine compounds, method for preparation thereof, and a pharamceutical composition comprising the same | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1991-10-16 | — | — | EP | disclosed |