SCHEMBL984436

SCHEMBL984436

C=C(C)C(=O)OCCCC(C)O[SiH](CC)CC

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
THRB P10828 1/20 0.44
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
HTT P42858 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ALDH1A1 P00352 2/20 0.32
FAAH O00519 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28927755 0.84 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT
SCHEMBL1782287 0.84 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT
SCHEMBL21810983 0.82 TSHR (0.47) TSHRTHRBPOLBAPEX1HTT
SCHEMBL20555113 0.82 TSHR (0.46) TSHRTHRBPOLBAPEX1HTT
SCHEMBL7641356 0.81 TSHR (0.45) TSHRTHRBPOLBAPEX1HTT
SCHEMBL30586248 0.79 TSHR (0.44) TSHRTHRBPOLBAPEX1HTT
SCHEMBL26980719 0.79 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL8523214 0.79 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL9223018 0.79 TSHR (0.53) TSHRTHRBTDP1ALDH1A1
SCHEMBL3363130 0.78 TSHR (0.51) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 225 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118221883-A Multilayer core-shell structure polymer and preparation method and application thereof 中化学科学技术研究有限公司 2024-06-21 CN claimed
CN-115181223-A Low-gloss matte auxiliary agent, preparation method thereof and formed body 铨盛聚碳科技股份有限公司 2022-10-14 CN claimed
CN-106866971-B Weather-resistant low-temperature-resistant organic silicon impact modifier and preparation method and application thereof 广东优科艾迪高分子材料有限公司 2020-05-05 CN claimed
US-12030973-B2 Thermoplastic resin composition and molded article of same TECHNO-UMG CO., LTD. (JP) 2024-07-09 US disclosed
US-11976189-B2 Thermoplastic resin composition and molded article TECHNO-UMG CO., LTD. (JP) 2024-05-07 US disclosed
US-20240092961-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE OF SAME TECHNO-UMG CO., LTD. (JP) 2024-03-21 US disclosed
US-20240052165-A1 RESIN COMPOSITION AND MOLDED BODY MITSUBISHI CHEMICAL CORPORATION (JP) 2024-02-15 US disclosed
US-20240043678-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE TECHNO-UMG CO., LTD. (JP) 2024-02-08 US disclosed
EP-4317229-A1 POLYORGANOSILOXANE-CONTAINING POLYMER, COMPOSITION, AND MOLDED ARTICLE Mitsubishi Chemical Corporation (JP) 2024-02-07 EP disclosed
EP-4317325-A1 RESIN COMPOSITION AND MOLDED BODY Mitsubishi Chemical Corporation (JP) 2024-02-07 EP disclosed
EP-4317309-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE THEREOF Techno-UMG Co., Ltd. (JP) 2024-02-07 EP disclosed
EP-0381239-A2 Impact-resistant resin MITSUBISHI RAYON COMPANY, LTD. (JP) 1990-08-08 EP disclosed
US-4918132-A Thermoplastic polyester resin composition MITSUBISHI RAYON COMPANY LIMITED (JP) 1990-04-17 US disclosed
US-4894415-A BLENDS, FRAFT COPOLYMERS, POLYALKYL (METH)ACRYLATE MITSUBISHI RAYON CO., LTD. (JP) 1990-01-16 US disclosed
US-4892900-A CONTAINING POLYSILOXANE GRAFT POLYMER, IMPROVED IMPACT STRENGTH MITSUBISHI RAYON CO., LTD. (JP) 1990-01-09 US disclosed
US-4888388-A BLENDS WITH POLYESTERS AND GRAFTED POLYSILOXANE-ACRYLIC POLYMERS MITSUBISHI RAYON COMPANY LIMITED (JP) 1989-12-19 US disclosed
EP-0308871-A2 Thermoplastic polyester resin composition MITSUBISHI RAYON CO., LTD. (JP) 1989-03-29 EP disclosed
US-4775712-A BLENDS WITH POLYSILOXANES-IMPACT STRENGTH, HEAT AND COLD RESISTANT, WEATHERPROOFING-MOLDING MATERIALS MITSUBISHI RAYON CO., LTD. (JP) 1988-10-04 US disclosed
US-4690986-A Impact-resistant thermoplastic polyorganosiloxane-based graft copolymer and process for producing same MITSUBISHI RAYON CO., LTD. (JP) 1987-09-01 US disclosed
EP-0231776-A1 Thermoplastic polyester resin composition MITSUBISHI RAYON CO., LTD. (JP) 1987-08-12 EP disclosed