SCHEMBL9844360

SCHEMBL9844360

COc1ccc(N2CC(CCCO)OC2=O)cc1

nearest known ligand 0.76

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 14/20 0.76
SIGMAR1 Q99720 6/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7294352 0.92 GRM2 (0.71) GRM2SIGMAR1
SCHEMBL1223003 0.87 GRM2 (0.67) GRM2SIGMAR1
SCHEMBL1223001 0.87 GRM2 (0.67) GRM2SIGMAR1
SCHEMBL2830353 0.86 GRM2 (1.00) GRM2
SCHEMBL7299902 0.84 GRM2 (0.71) GRM2SIGMAR1
SCHEMBL9844018 0.84 GRM2 (0.71) GRM2SIGMAR1
SCHEMBL8798938 0.82 GRM2 (0.68) GRM2SIGMAR1
SCHEMBL7293315 0.81 GRM2 (0.67) GRM2SIGMAR1
SCHEMBL28922850 0.81 GRM2 (0.67) GRM2SIGMAR1
SCHEMBL6861651 0.81 GRM2 (0.67) GRM2SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0443197-A2 Oxazolidinones MERCK PATENT GmbH (DE) 1991-08-28 EP disclosed