Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | AGTR1 | P30556 | 6/20 | 0.49 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.47 |
| ▸ | APLNR | P35414 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9843965 | 0.88 | CYP19A1 (0.46) | PPARGACHEAGTR1AGTR2 | |
| SCHEMBL9843897 | 0.84 | PPARG (0.58) | PPARGACHEAGTR1AGTR2 | |
| SCHEMBL4305127 | 0.84 | PPARG (0.58) | PPARGACHEAGTR1AGTR2 | |
| SCHEMBL1888053 | 0.83 | PPARG (0.57) | PPARGACHEAGTR1AGTR2 | |
| SCHEMBL9843913 | 0.83 | PPARG (0.60) | PPARGACHEAGTR1AGTR2 | |
| SCHEMBL9844118 | 0.82 | PPARG (0.52) | PPARGACHEAGTR1AGTR2 | |
| SCHEMBL9337497 | 0.82 | PPARG (0.56) | PPARGACHEAGTR1AGTR2APLNR | |
| SCHEMBL9844140 | 0.81 | PPARG (0.56) | PPARGACHEAGTR1AGTR2 | |
| SCHEMBL9843750 | 0.81 | PPARG (0.56) | PPARGACHEAGTR1AGTR2 | |
| SCHEMBL9843823 | 0.81 | PPARG (0.56) | PPARGACHEAGTR1AGTR2APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407342-A2 | Pyrimidine derivatives | CIBA-GEIGY AG (CH) | 1991-01-09 | — | — | EP | disclosed |