Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8844966 | 0.81 | TDP1 (0.60) | APEX1TDP1MAPTL3MBTL1NPSR1 | |
| SCHEMBL10898848 | 0.80 | APEX1 (0.47) | APEX1TDP1MAPTL3MBTL1NPSR1 | |
| SCHEMBL11148523 | 0.80 | APEX1 (0.45) | APEX1TDP1MAPTL3MBTL1NPSR1 | |
| SCHEMBL76989 | 0.79 | APEX1 (0.50) | APEX1TDP1MAPTL3MBTL1NPSR1 | |
| SCHEMBL29350333 | 0.79 | APEX1 (0.50) | APEX1TDP1MAPTL3MBTL1NPSR1 | |
| SCHEMBL18355245 | 0.79 | APEX1 (0.50) | APEX1TDP1MAPTL3MBTL1NPSR1 | |
| SCHEMBL18690279 | 0.79 | APEX1 (0.52) | APEX1TDP1MAPTL3MBTL1NPSR1 | |
| SCHEMBL27577575 | 0.77 | APEX1 (0.48) | APEX1TDP1MAPTL3MBTL1NPSR1 | |
| SCHEMBL673853 | 0.76 | TSHR (0.37) | TDP1L3MBTL1ALDH1A1CYP2C19RAB9A | |
| Benzamide SCHEMBL21771957 | 0.75 | TDP1 (0.54) | APEX1TDP1MAPTL3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416321-A1 | Crystalline polyolefin composition | Chisso Corporation (JP) | 1991-03-13 | — | — | EP | disclosed |