Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | F2R | P25116 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844733 | 1.00 | HTR2A (0.40) | HTR2AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL9844738 | 1.00 | HTR2A (0.40) | HTR2AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL8946281 | 0.85 | HTR2A (0.39) | HTR2AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL8946289 | 0.85 | HTR2A (0.39) | HTR2AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL8946284 | 0.85 | HTR2A (0.39) | HTR2AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL8946312 | 0.81 | KDM4E (0.43) | HTR2AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL8946310 | 0.81 | KDM4E (0.43) | HTR2AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL8946314 | 0.81 | KDM4E (0.43) | HTR2AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL8946368 | 0.76 | MAPT (0.52) | HTR2AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL8946374 | 0.76 | MAPT (0.52) | HTR2AKDM4EALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409410-A1 | Indenoindole compounds | UNIVERSITY OF BATH (GB) | 1991-01-23 | — | — | EP | disclosed |