Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6885967 | 0.80 | MAPT (0.69) | MAPTCACNA1BAPBA1APPCYP3A4 | |
| SCHEMBL36139 | 0.80 | MAPT (0.69) | MAPTCACNA1BAPBA1APPCYP3A4 | |
| SCHEMBL36375 | 0.80 | MAPT (0.69) | MAPTCACNA1BAPBA1APPCYP3A4 | |
| SCHEMBL36140 | 0.80 | MAPT (0.69) | MAPTCACNA1BAPBA1APPCYP3A4 | |
| SCHEMBL7809914 | 0.78 | MAPT (0.67) | MAPTCACNA1BAPBA1APPCYP3A4 | |
| Ethylene SCHEMBL28241615 | 0.78 | MAPT (0.67) | MAPTCACNA1BAPBA1APPCYP3A4 | |
| SCHEMBL7809907 | 0.78 | MAPT (0.67) | MAPTCACNA1BAPBA1APPCYP3A4 | |
| SCHEMBL2945906 | 0.76 | MAPT (0.59) | MAPTCACNA1BAPBA1APPCYP3A4 | |
| SCHEMBL2945907 | 0.76 | MAPT (0.59) | MAPTCACNA1BAPBA1APPCYP3A4 | |
| SCHEMBL2755754 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0448848-A1 | Hydroformylation of olefins | ENIRICERCHE S.p.A. (IT) | 1991-10-02 | — | — | EP | claimed |
| EP-0448848-A1 | Hydroformylation of olefins | ENIRICERCHE S.p.A. (IT) | 1991-10-02 | — | — | EP | disclosed |