Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14760916 | 0.80 | MAPT (0.51) | MAPTKDM4EALOX15HPGDHSD17B10 | |
| SCHEMBL28137387 | 0.78 | KDM4E (0.84) | MAPTKDM4EALOX15HPGDHSD17B10 | |
| SCHEMBL29415000 | 0.78 | KDM4E (0.84) | MAPTKDM4EALOX15HPGDHSD17B10 | |
| SCHEMBL9639024 | 0.75 | KDM4E (0.63) | MAPTKDM4EALOX15HPGDHSD17B10 | |
| SCHEMBL9714980 | 0.74 | KDM4E (0.71) | MAPTKDM4EALOX15HPGDHSD17B10 | |
| SCHEMBL9715029 | 0.74 | MAPT (0.71) | MAPTKDM4EALOX15HPGDHSD17B10 | |
| SCHEMBL12732139 | 0.74 | KMT2A (0.62) | MAPTESR1ESR2KMT2ARAB9A | |
| SCHEMBL28683507 | 0.73 | MAPT (0.69) | MAPTKDM4EALOX15HPGDHSD17B10 | |
| SCHEMBL29415002 | 0.73 | MAPT (0.69) | MAPTKDM4EALOX15HPGDHSD17B10 | |
| SCHEMBL29415034 | 0.73 | MAPT (0.66) | MAPTKDM4EALOX15HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416288-A2 | Reduction of acidity of polyesters by melt reaction endcapping | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0414009-A2 | Reduction of acidity of polyesters by melt reaction endcapping with dialkyloxalate | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-02-27 | — | — | EP | disclosed |
| EP-0414008-A2 | Reduction of acidity of polyesters by melt reaction endcapping with enamines or schiff bases | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-02-27 | — | — | EP | disclosed |