Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.33 |
| ▸ | TUBB | P07437 | 2/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.33 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.33 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.33 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845326 | 1.00 | ESR1 (0.39) | ESR1ESR2MAPTSERPINE1HPGD | |
| SCHEMBL9845347 | 0.85 | ESR1 (0.40) | ESR1ESR2MAPTSERPINE1HPGD | |
| SCHEMBL9845344 | 0.85 | ESR1 (0.40) | ESR1ESR2MAPTSERPINE1HPGD | |
| SCHEMBL9845332 | 0.84 | MAPT (0.33) | MAPTHPGDTDP1ALDH1A1SLC6A4 | |
| SCHEMBL9845339 | 0.84 | MAPT (0.33) | MAPTHPGDTDP1ALDH1A1SLC6A4 | |
| SCHEMBL9845376 | 0.84 | MAPT (0.33) | MAPTHPGDTDP1ALDH1A1KDM4E | |
| SCHEMBL9845380 | 0.84 | MAPT (0.33) | MAPTHPGDTDP1ALDH1A1KDM4E | |
| SCHEMBL9845373 | 0.80 | HMGCR (0.34) | MAPTHPGDTDP1 | |
| SCHEMBL9845364 | 0.80 | HMGCR (0.34) | MAPTHPGDTDP1 | |
| SCHEMBL9845370 | 0.80 | HMGCR (0.34) | MAPTHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0420266-A2 | Chromene or thiochromene derivatives, process for preparing the same, intermediate therefor, pharmaceutical compositions containing said derivatives and the use of said derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1991-04-03 | — | — | EP | disclosed |