Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL986114 | 0.99 | CNR2 (0.43) | CNR2CNR1KDM5AKDM4CBRD4 | |
| Hydrochloric Acid SCHEMBL985799 | 0.94 | CNR2 (0.42) | CNR2CNR1KDM5AKDM4CBRD4 | |
| SCHEMBL983561 | 0.91 | CNR2 (0.48) | CNR2CNR1 | |
| SCHEMBL985434 | 0.90 | CNR2 (0.43) | CNR2CNR1 | |
| Hydrochloric Acid SCHEMBL984193 | 0.88 | CNR2 (0.40) | CNR2CNR1KDM4CWDR5SCN9A | |
| SCHEMBL986222 | 0.87 | CNR2 (0.40) | CNR2CNR1WDR5SCN9A | |
| Hydrochloric Acid SCHEMBL985232 | 0.86 | CNR2 (0.40) | CNR2CNR1WDR5SCN9A | |
| Hydrochloric Acid SCHEMBL985106 | 0.86 | CNR2 (0.40) | CNR2CNR1KDM4CWDR5SCN9A | |
| SCHEMBL981513 | 0.86 | CNR2 (0.46) | CNR2CNR1KDM4CBRD4KDM2B | |
| SCHEMBL981819 | 0.85 | CNR2 (0.43) | CNR2CNR1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445501-B2 | Substituted 7-carboxamido-pyrrolo[3,2-d]pyrimidines | TAKEDA GMBH (DE) | 2013-05-21 | — | — | US | disclosed |
| US-20110021479-A1 | PYRROLOPYRIMIDINECARBOXAMIDES | NYCOMED GMBH (DE) | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021479-A1 | PYRROLOPYRIMIDINECARBOXAMIDES | PDE5A, PDE3A, PDE2A | CNR2 1647/4885CNR1 2115/4885KDM5A 263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.