SCHEMBL9846494

SCHEMBL9846494

O=C1c2cccc(Sc3ccccc3)c2C(=O)c2cccc(Cl)c21

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.73
NSD2 O96028 2/20 0.73
KDM4E B2RXH2 1/20 0.73
MAPK1 P28482 1/20 0.73
ADORA2A P29274 3/20 0.48
ALDH1A1 P00352 2/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
TTR P02766 1/20 0.39
MAPK14 Q16539 2/20 0.39
MAPK13 O15264 1/20 0.39
MAPK12 P53778 1/20 0.39
MAPK11 Q15759 1/20 0.39
BCL2 P10415 1/20 0.38
PDE7A Q13946 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
SIRT1 Q96EB6 1/20 0.37
PTPN1 P18031 1/20 0.36
CDC25A P30304 1/20 0.36
CDC25B P30305 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11538344 0.95 MAPT (0.81) MAPTNSD2KDM4EMAPK1ADORA2A
SCHEMBL4465042 0.90 MAPT (0.89) MAPTNSD2KDM4EMAPK1ADORA2A
SCHEMBL285567 0.86 MAPT (0.89) MAPTNSD2KDM4EMAPK1ADORA2A
SCHEMBL30475313 0.86 MAPT (0.89) MAPTNSD2KDM4EMAPK1ADORA2A
Anthraquinone SCHEMBL11411972 0.86 MAPT (0.89) MAPTNSD2KDM4EMAPK1ADORA2A
SCHEMBL13797742 0.86 NSD2 (0.54) MAPTNSD2KDM4EMAPK1ADORA2A
SCHEMBL13797721 0.86 MAPT (0.54) MAPTNSD2KDM4EMAPK1ADORA2A
SCHEMBL22827087 0.85 MAPT (0.86) MAPTNSD2KDM4EMAPK1ADORA2A
SCHEMBL29365916 0.84 MAPT (1.00) MAPTNSD2KDM4EMAPK1ADORA2A
SCHEMBL3459973 0.84 MAPT (1.00) MAPTNSD2KDM4EMAPK1ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0432095-A1 Anthraquino vat dyestuffs, their preparation and their use CIBA-GEIGY AG (CH) 1991-06-12 EP disclosed
EP-0274458-B1 ANTHRAQUINONE VAT DYESTUFFS, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1990-09-19 EP disclosed
EP-0274356-B1 VATTABLE 2-ARYL-4,6-DIAMINOPYRIMIDINE CIBA-GEIGY AG (CH) 1990-05-16 EP disclosed
US-4845220-A Vattable 2-aryl-4,6-diaminopyrimidines CIBA-GEIGY CORPORATION 1989-07-04 US disclosed
EP-0274458-A1 Anthraquinone vat dyestuffs, their preparation and their use CIBA-GEIGY AG (CH) 1988-07-13 EP disclosed
EP-0059036-B1 PLEOCHROIC ANTHRAQUINONE DYES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-07-29 EP disclosed
EP-0059095-B1 LIQUID CRYSTAL MATERIALS COMPRISING PLEOCHROIC DYES The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1987-04-29 EP disclosed
EP-0049035-B1 ORGANIC COMPOSITIONS SUITABLE FOR A GUEST-HOST LIQUID CRYSTAL DEVICE The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1985-10-23 EP disclosed
EP-0155345-A2 Pleochroic anthraquinone dyes The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1985-09-25 EP disclosed
EP-0142617-A1 Pleochroic anthraquinone dyes IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-05-29 EP disclosed
US-4464282-A ANTHRAQUINONE PLEOCHROIC DYE FOR LIQUID CRYSTALS THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITIAN AND NORTHERN IRELAND (GB) 1984-08-07 US disclosed
US-4455253-A FOR LIQUID CRYSTAL DISPLAYS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-06-19 US disclosed
US-4446047-A Pleochroic anthraquinone dyes IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-05-01 US disclosed
US-4405211-A CLOCKS; DISPLAYING; OPTICAL APPARATUS; ELECTRICAL THIN FILMS THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1983-09-20 US disclosed
EP-0059095-A1 Liquid crystal materials comprising pleochroic dyes The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1982-09-01 EP disclosed
EP-0059036-A1 Pleochroic anthraquinone dyes IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-09-01 EP disclosed
EP-0049035-A1 Organic compositions suitable for a guest-host liquid crystal device The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1982-04-07 EP disclosed
US-4126626-A DYES, POLYESTERS CIBA-GEIGY CORPORATION (US) 1978-11-21 US disclosed
US-3972881-A VAT, CELLULOSE CIBA-GEIGY CORPORATION (US) 1976-08-03 US disclosed
US-3935208-A NATURAL OR REGENERATED CELLULOSE ALTERMATT HANS 1976-01-27 US disclosed