Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | ACR | P10323 | 1/20 | 0.44 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9353455 | 0.83 | TDP1 (0.54) | USP2HPGDSMN1; SMN2TDP1MAPT | |
| SCHEMBL9241160 | 0.83 | TDP1 (0.54) | USP2HPGDSMN1; SMN2TDP1MAPT | |
| SCHEMBL27352197 | 0.83 | TDP1 (0.54) | USP2HPGDSMN1; SMN2TDP1MAPT | |
| SCHEMBL9353461 | 0.83 | TDP1 (0.54) | USP2HPGDSMN1; SMN2TDP1MAPT | |
| SCHEMBL18073 | 0.83 | TDP1 (0.54) | USP2HPGDSMN1; SMN2TDP1MAPT | |
| SCHEMBL27323462 | 0.83 | USP2 (0.50) | USP2HPGDSMN1; SMN2TDP1MAPT | |
| SCHEMBL8763081 | 0.80 | TDP1 (0.52) | USP2HPGDSMN1; SMN2TDP1MAPT | |
| Bicarbonate SCHEMBL1393750 | 0.80 | TDP1 (0.52) | USP2HPGDSMN1; SMN2TDP1MAPT | |
| SCHEMBL1362173 | 0.80 | TDP1 (0.52) | USP2HPGDSMN1; SMN2TDP1MAPT | |
| SCHEMBL10945396 | 0.80 | TDP1 (0.52) | USP2HPGDSMN1; SMN2TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432095-A1 | Anthraquino vat dyestuffs, their preparation and their use | CIBA-GEIGY AG (CH) | 1991-06-12 | — | — | EP | disclosed |
| EP-0274458-B1 | ANTHRAQUINONE VAT DYESTUFFS, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1990-09-19 | — | — | EP | disclosed |
| EP-0274458-A1 | Anthraquinone vat dyestuffs, their preparation and their use | CIBA-GEIGY AG (CH) | 1988-07-13 | — | — | EP | disclosed |