Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | BCL9 | O00512 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5827968 | 0.89 | HTR2A (0.80) | HTR2AALDH1A1GAAMAOBRAB9A | |
| SCHEMBL6588959 | 0.87 | HTR2A (0.66) | HTR2AMAPTALDH1A1GAAMAOB | |
| SCHEMBL6594172 | 0.85 | HTR2A (0.74) | HTR2AMAPTALDH1A1GAAMAOB | |
| SCHEMBL12524469 | 0.85 | HTR2A (0.74) | HTR2AMAPTALDH1A1GAAMAOB | |
| SCHEMBL4112112 | 0.85 | HTR2A (0.74) | HTR2AMAPTALDH1A1GAAMAOB | |
| SCHEMBL14621621 | 0.85 | HTR2A (0.74) | HTR2AALDH1A1GAAMAOBRAB9A | |
| Water SCHEMBL10938430 | 0.84 | HTR2A (0.73) | HTR2AMAPTALDH1A1GAAMAOB | |
| Water SCHEMBL10938437 | 0.84 | HTR2A (0.73) | HTR2AMAPTALDH1A1GAAMAOB | |
| SCHEMBL4124290 | 0.83 | HTR2A (0.71) | HTR2AMAPTMAOBMEN1KMT2A | |
| SCHEMBL20467771 | 0.83 | HTR2A (0.71) | HTR2AMAPTALDH1A1GAAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429232-A1 | N-substituted derivatives of 3R,4R-ethyl-[(1-methyl-1H-imidazol-5-yl)methyl]-2-pyrrolidinone | ALLERGAN, INC. (US) | 1991-05-29 | — | — | EP | disclosed |