Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | BCL9 | O00512 | 1/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MGLL | Q99685 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16203199 | 0.89 | HTR2A (0.53) | HTR2ABCL9CTNNB1GAAMGLL | |
| SCHEMBL21058129 | 0.89 | BCL9 (0.57) | HTR2ABCL9CTNNB1GAAMGLL | |
| SCHEMBL21058146 | 0.89 | BCL9 (0.57) | HTR2ABCL9CTNNB1GAAMGLL | |
| SCHEMBL21058130 | 0.89 | BCL9 (0.57) | HTR2ABCL9CTNNB1GAAMGLL | |
| SCHEMBL21097658 | 0.86 | BCL9 (0.56) | HTR2ABCL9CTNNB1GAAMGLL | |
| SCHEMBL12375535 | 0.86 | BCL9 (0.56) | HTR2ABCL9CTNNB1GAAMGLL | |
| SCHEMBL21097204 | 0.86 | BCL9 (0.56) | HTR2ABCL9CTNNB1GAAMGLL | |
| SCHEMBL13863047 | 0.85 | HTR2A (0.53) | HTR2ABCL9CTNNB1GAAMGLL | |
| SCHEMBL1242235 | 0.84 | HTR2A (0.54) | HTR2ABCL9CTNNB1GAAMGLL | |
| SCHEMBL30209699 | 0.83 | BCL9 (0.54) | HTR2ABCL9CTNNB1GAAMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429232-A1 | N-substituted derivatives of 3R,4R-ethyl-[(1-methyl-1H-imidazol-5-yl)methyl]-2-pyrrolidinone | ALLERGAN, INC. (US) | 1991-05-29 | — | — | EP | disclosed |