Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3538057 | 1.00 | EPHX1 (0.52) | EPHX1TP53ALDH1A1NPSR1THRB | |
| SCHEMBL17398017 | 0.88 | CA14 (0.44) | EPHX1TP53ALDH1A1NPSR1THRB | |
| SCHEMBL19942011 | 0.82 | TP53 (0.62) | EPHX1TP53ALDH1A1NPSR1THRB | |
| SCHEMBL6862095 | 0.82 | TP53 (0.62) | EPHX1TP53ALDH1A1NPSR1THRB | |
| SCHEMBL27737037 | 0.82 | TP53 (0.49) | EPHX1TP53ALDH1A1NPSR1THRB | |
| SCHEMBL19941727 | 0.82 | TP53 (0.62) | EPHX1TP53ALDH1A1NPSR1THRB | |
| SCHEMBL14679339 | 0.80 | TP53 (0.47) | EPHX1TP53ALDH1A1NPSR1THRB | |
| SCHEMBL3996792 | 0.80 | TP53 (0.47) | EPHX1TP53ALDH1A1NPSR1THRB | |
| SCHEMBL6592409 | 0.80 | TP53 (0.47) | EPHX1TP53ALDH1A1NPSR1THRB | |
| SCHEMBL1874858 | 0.80 | TP53 (0.47) | EPHX1TP53ALDH1A1NPSR1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417760-A2 | Phenylalkanoyl substituted imidazo[4,5-c] pyridines | G.D. Searle & Co. (US) | 1991-03-20 | — | — | EP | disclosed |
| US-4988707-A | Platelet activating factor, antiinflammatory agents, cardiovascular disorders and treatment of asthma | G. D. SEARLE & CO. (US) | 1991-01-29 | — | — | US | disclosed |