Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3145647 | 0.88 | KDM4E (0.42) | GRIK1AKR1C3MCL1ALDH1A1KDM4E | |
| SCHEMBL10482273 | 0.80 | AKR1C3 (0.45) | GRIK1AKR1C3MCL1ALDH1A1KDM4E | |
| Ethylene Glycol SCHEMBL10395022 | 0.77 | AKR1C3 (0.52) | GRIK1AKR1C3MCL1ALDH1A1KDM4E | |
| SCHEMBL693055 | 0.74 | AKR1C3 (0.59) | GRIK1AKR1C3MCL1ALDH1A1KDM4E | |
| SCHEMBL16462 | 0.74 | AKR1C3 (0.59) | GRIK1AKR1C3MCL1ALDH1A1KDM4E | |
| SCHEMBL10454886 | 0.74 | AKR1C3 (0.59) | GRIK1AKR1C3MCL1ALDH1A1KDM4E | |
| Acrylic Acid SCHEMBL448096 | 0.73 | AKR1C3 (0.50) | GRIK1AKR1C3MCL1ALDH1A1KDM4E | |
| SCHEMBL6875649 | 0.72 | KDM4E (0.42) | GRIK1MCL1ALDH1A1KDM4ELMNA | |
| Propylene Glycol SCHEMBL10395479 | 0.72 | GRIK1 (0.47) | GRIK1AKR1C3MCL1ALDH1A1KDM4E | |
| SCHEMBL8445784 | 0.72 | AKR1C3 (0.38) | AKR1C3LMNATDP1HTTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0406702-A1 | Preparation of polyurethane foams without using inert blowing agents | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) | 1991-01-09 | — | — | EP | disclosed |