Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | NAAA | Q02083 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709873 | 0.88 | TSHR (0.47) | TSHREPHX2NAAAMAPK1MAPT | |
| SCHEMBL28342738 | 0.82 | NPSR1 (0.53) | TSHREPHX2NAAAMAPK1MAPT | |
| SCHEMBL28825961 | 0.81 | TSHR (0.43) | TSHREPHX2NAAAMAPK1MAPT | |
| SCHEMBL634781 | 0.81 | EPHX2 (0.43) | TSHREPHX2 | |
| SCHEMBL634780 | 0.81 | EPHX2 (0.54) | TSHREPHX2NAAAMAPK1MAPT | |
| SCHEMBL5709969 | 0.80 | TSHR (0.48) | TSHREPHX2NAAAMAPK1MAPT | |
| SCHEMBL28342749 | 0.80 | EPHX2 (0.48) | TSHREPHX2NAAAMAPK1MAPT | |
| SCHEMBL7662341 | 0.80 | TSHR (0.57) | TSHREPHX2NAAAMAPK1GAA | |
| SCHEMBL7654322 | 0.80 | TSHR (0.57) | TSHREPHX2NAAAMAPK1GAA | |
| SCHEMBL7658530 | 0.80 | TSHR (0.57) | TSHREPHX2NAAAMAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0457505-A2 | Pyrimidine derivatives and their use as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-11-21 | — | — | EP | disclosed |