Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 12/20 | 0.67 |
| ▸ | GPBAR1 | Q8TDU6 | 8/20 | 0.67 |
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | GMNN | O75496 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8870891 | 0.90 | CYSLTR1 (0.71) | CYSLTR1GPBAR1CYSLTR2MAPK1ALOX5 | |
| Hydrochloric Acid SCHEMBL9688757 | 0.86 | CYSLTR1 (0.61) | CYSLTR1GPBAR1CYSLTR2MAPK1ALOX5 | |
| SCHEMBL9081248 | 0.85 | CYSLTR1 (0.70) | CYSLTR1GPBAR1CYSLTR2MAPK1ALOX5 | |
| SCHEMBL25214519 | 0.84 | CYSLTR1 (0.79) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL30443236 | 0.84 | CYSLTR1 (0.79) | CYSLTR1GPBAR1CYSLTR2 | |
| Hydrochloric Acid SCHEMBL9689596 | 0.83 | CYSLTR1 (0.63) | CYSLTR1GPBAR1CYSLTR2MAPK1ALOX5 | |
| SCHEMBL10512475 | 0.82 | PDE10A (0.77) | CYSLTR1GPBAR1CYSLTR2CYP1A2PDE10A | |
| SCHEMBL10635186 | 0.82 | CYSLTR1 (0.64) | CYSLTR1GPBAR1CYSLTR2MAPK1ALOX5 | |
| SCHEMBL10639069 | 0.82 | CYSLTR1 (0.68) | CYSLTR1GPBAR1CYSLTR2MAPK1ALOX5 | |
| SCHEMBL10769450 | 0.82 | CYSLTR1 (0.94) | CYSLTR1GPBAR1CYSLTR2MAPK1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414078-A2 | Disubstituted (quinolin-2-yl-methoxy)-phenylacetic acid derivatives | BAYER AG (DE) | 1991-02-27 | — | — | EP | disclosed |
| EP-0344519-A1 | Substituted 4-(quinolin-2-yl-methoxy)phenyl-acetic-acid derivatives | BAYER AG (DE) | 1989-12-06 | — | — | EP | disclosed |