SCHEMBL9847751

SCHEMBL9847751

CCCC(c1cc(C(C)(C)C)c(Oc2ccc(C#N)c(C#N)c2)cc1C)c1cc(C(C)(C)C)c(Oc2ccc(C#N)c(C#N)c2)cc1C

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
ALOX15 P16050 1/20 0.47
CYP2C19 P33261 1/20 0.47
AR P10275 19/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5150318 0.80 TP53 (0.52) TP53CYP2D6CYP2C9ALOX15CYP2C19
SCHEMBL9847760 0.79 AR (0.50) AR
SCHEMBL9847759 0.78 TP53 (0.50) TP53CYP2D6CYP2C9ALOX15CYP2C19
SCHEMBL3419449 0.77 TP53 (0.57) TP53CYP2D6CYP2C9ALOX15CYP2C19
SCHEMBL8990309 0.74 TP53 (0.44) TP53CYP2D6CYP2C9ALOX15CYP2C19
SCHEMBL8990487 0.73 TP53 (0.43) TP53CYP2D6CYP2C9ALOX15CYP2C19
SCHEMBL9847755 0.73 AR (0.48) AR
SCHEMBL8990354 0.72 TP53 (0.42) TP53CYP2D6CYP2C9ALOX15CYP2C19
SCHEMBL9847778 0.72 AR (0.49) AR
SCHEMBL8623452 0.70 AR (0.53) AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0413415-A1 Carboxylic acids and derivates thereof The British Petroleum Company p.l.c. (GB) 1991-02-20 EP disclosed