Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.71 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | HRH1 | P35367 | 4/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8502036 | 1.00 | TAAR1 (0.71) | TAAR1MAOATHRBHRH1IDO1 | |
| SCHEMBL8605570 | 0.98 | TAAR1 (0.74) | TAAR1MAOATHRBHRH1IDO1 | |
| Dimethylamine SCHEMBL9872976 | 0.93 | TAAR1 (0.67) | TAAR1MAOATHRBHRH1IDO1 | |
| SCHEMBL2673980 | 0.92 | TAAR1 (0.77) | TAAR1MAOATHRBIDO1HRH3 | |
| Hydrochloric Acid SCHEMBL1028929 | 0.90 | TAAR1 (0.74) | TAAR1MAOATHRBIDO1HRH3 | |
| SCHEMBL8095693 | 0.90 | TAAR1 (0.65) | TAAR1IDO1HRH3NAAA | |
| SCHEMBL8092438 | 0.90 | TAAR1 (0.65) | TAAR1IDO1HRH3NAAA | |
| SCHEMBL8093918 | 0.90 | TAAR1 (0.65) | TAAR1IDO1HRH3NAAA | |
| SCHEMBL8101532 | 0.90 | TAAR1 (0.65) | TAAR1IDO1HRH3NAAA | |
| SCHEMBL8086943 | 0.90 | TAAR1 (0.65) | TAAR1IDO1HRH3NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415123-A2 | 1-Phenylalkyl-3-phenylurea derivatives | Mitsubishi Chemical Corporation (JP) | 1991-03-06 | — | — | EP | disclosed |