SCHEMBL9848528

SCHEMBL9848528

C1=CCC(c2ccccc2CCc2ccccc2)=C1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.43
IDO2 Q6ZQW0 1/20 0.43
NR1H2 P55055 1/20 0.41
NR1H3 Q13133 1/20 0.41
HTR1A P08908 2/20 0.39
DRD2 P14416 2/20 0.39
ABCB1 P08183 3/20 0.37
TSHR P16473 2/20 0.37
HTT P42858 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
USP2 O75604 1/20 0.37
ALOX15 P16050 1/20 0.37
PPARA Q07869 1/20 0.36
CREBBP Q92793 1/20 0.36
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
ATM Q13315 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28287829 0.80 CYP2D6 (0.36) L3MBTL1ALDH1A1MAPT
Biphenyl SCHEMBL27504184 0.80 NR1H2 (0.35) NR1H2NR1H3PPARA
SCHEMBL3213007 0.79 PDCD1 (0.42)
SCHEMBL28006187 0.77
SCHEMBL30747866 0.77 IDO1 (0.56) IDO1IDO2NR1H2NR1H3HTR1A
SCHEMBL30626777 0.77
SCHEMBL7100251 0.76
SCHEMBL3213454 0.76 HIF1A (0.39) HTTL3MBTL1ALDH1A1MAPTATM
Hydrochloric Acid SCHEMBL3202318 0.75
SCHEMBL7108452 0.74 MAOB (0.43) ALOX15ALDH1A1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100516120-C Olefin block copolymers, production processes of same and use thereof MITSUI CHEMICALS INC (JP) 2009-07-22 CN disclosed
CN-100509872-C Olefin polymerization catalyst composition comprising group 13 amide derivatives DOW GLOBAL TECHNOLOGIES INC (US) 2009-07-08 CN disclosed
CN-100398597-C Ethylene copolymer composition and use thereof MITSUI CHEMICALS INC (JP) 2008-07-02 CN disclosed
CN-100351275-C Morphology controlled olefin polymerization process DOW GLOBAL TECHNOLOGIES INC (US) 2007-11-28 CN disclosed
CN-101070360-A Polyethylene resins with bimodal molecular weight distribution UNIVATION TECH LLC (US) 2007-11-14 CN disclosed
CN-101062959-A Method of making mixed ziegler-natta/metallocece catalysts EXXONMOBIL CHEM PATENTS INC (US) 2007-10-31 CN disclosed
CN-100343291-C Polyethylene resins with bimodal molecular weight distribution and use EXXONMOBIL CHEM PATENTS INC (US) 2007-10-17 CN disclosed
CN-1319995-C Reactor wall coating and method of forming the same UNIVATION TECH LLC (US) 2007-06-06 CN disclosed
CN-1313526-C Ethylene copolymer composition and use thereof MITSUI CHEMICALS INC (JP) 2007-05-02 CN disclosed
CN-1283669-C Control of solution catalyst droplets UNION CARBIDE CHEM PLASTIC (US) 2006-11-08 CN disclosed
CN-1256703-A Ethylene copolymer composition and use thereof MITSUI CHEMICALS INC (JP) 2000-06-14 CN disclosed
CN-1226563-A Ethylene/alpha-olefin copolymer and process for producing the same MITSUI CHEMICALS INC (JP) 1999-08-25 CN disclosed
CN-1042433-C Process for producing olefin polymer MITSUI PETROCHEMICAL IND (JP) 1999-03-10 CN disclosed
CN-1040762-C Catalysts for olefin polymerization and application thereof MITSUI PETROCHEMICAL IND (JP) 1998-11-18 CN disclosed
CN-1135489-A Dry-prepolymerized olefine polymer catalyst and preparation method thereof, and gas-phase olefines polymerization method MITSUI PETROCHEMICAL IND (JP) 1996-11-13 CN disclosed
CN-1032008-C Addition polymerization catalyst with oxidative activation DOW CHEMICAL CO (US) 1996-06-12 CN disclosed
CN-1086826-A Catalyst for olefines polymerizing and uses thereof MITSUI PETROCHEMICAL IND (JP) 1994-05-18 CN disclosed
CN-1057845-A Addition polymerization catalyst with oxidation activity DOW CHEMICAL CO (US) 1992-01-15 CN disclosed
CN-1055935-A Ethylene copolymer, process for producing hydrocarbon olefin polymer, and catalyst for olefin polymerization MITSUI PETROCHEMICAL IND (JP) 1991-11-06 CN disclosed
EP-0421659-A2 Process for preparation of syndiotactic vinyl aromatic polymers THE DOW CHEMICAL COMPANY (US) 1991-04-10 EP disclosed