Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.66 |
| ▸ | SMARCA2 | P51531 | 5/20 | 0.39 |
| ▸ | SMARCA4 | P51532 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7611582 | 0.80 | SLC6A2 (1.00) | SLC6A2 | |
| SCHEMBL9445558 | 0.78 | SLC6A2 (0.51) | SLC6A2KDM4ENQO2MEN1KMT2A | |
| Oxalic Acid SCHEMBL7610219 | 0.73 | SLC6A2 (0.84) | SLC6A2KDM4EMEN1KMT2A | |
| SCHEMBL9445636 | 0.73 | SLC6A2 (0.57) | SLC6A2KDM4ENQO2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10403490 | 0.71 | SLC6A2 (0.56) | SLC6A2TGFBR1 | |
| SCHEMBL9445621 | 0.70 | SLC6A2 (0.51) | SLC6A2KDM4ENQO2MEN1KMT2A | |
| SCHEMBL7612596 | 0.70 | SLC6A2 (0.62) | SLC6A2TGFBR1 | |
| SCHEMBL9445638 | 0.69 | SLC6A2 (0.65) | SLC6A2SRCTGFBR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7614144 | 0.69 | SLC6A2 (0.60) | SLC6A2TGFBR1 | |
| SCHEMBL7232050 | 0.68 | SLC6A2 (0.68) | SLC6A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417584-A2 | N-substituted-4-pyrimidinamines and -pyrimidindiamines, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-03-20 | — | — | EP | claimed |