Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8952814 | 1.00 | HMGCR (0.37) | HMGCRCTSA | |
| SCHEMBL8952832 | 1.00 | HMGCR (0.37) | HMGCRCTSA | |
| SCHEMBL8953140 | 0.92 | HMGCR (0.45) | HMGCR | |
| SCHEMBL8953107 | 0.92 | HMGCR (0.45) | HMGCR | |
| SCHEMBL8953018 | 0.85 | HMGCR (0.43) | HMGCR | |
| SCHEMBL9849235 | 0.85 | HMGCR (0.43) | HMGCR | |
| SCHEMBL8953004 | 0.85 | HMGCR (0.43) | HMGCR | |
| SCHEMBL8952761 | 0.84 | HMGCR (0.45) | HMGCR | |
| SCHEMBL8952743 | 0.84 | HMGCR (0.45) | HMGCR | |
| SCHEMBL8952874 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0444533-A2 | Quinoline and pyridine anchors for HMG-CoA reductase inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1991-09-04 | — | — | EP | disclosed |