Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 0.50 |
| ▸ | CCNC | P24863 | 1/20 | 0.48 |
| ▸ | CDK8 | P49336 | 1/20 | 0.48 |
| ▸ | SOD1 | P00441 | 2/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.45 |
| ▸ | QPCT | Q16769 | 3/20 | 0.45 |
| ▸ | PLK4 | O00444 | 1/20 | 0.45 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | FLT4 | P35916 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | CLK2 | P49760 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.45 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16013594 | 0.79 | FERMT2 (0.66) | CCNCCDK8CCR1PLK4DYRK3 | |
| SCHEMBL5549300 | 0.76 | FERMT2 (0.68) | CCNCCDK8CCR1PLK4DYRK3 | |
| SCHEMBL1861045 | 0.76 | CCNC (0.55) | CCNCCDK8CCR1PLK4DYRK3 | |
| SCHEMBL1855953 | 0.76 | CCNC (0.55) | CCNCCDK8CCR1PLK4DYRK3 | |
| SCHEMBL31594748 | 0.74 | FERMT2 (0.61) | CCNCCDK8CCR1PLK4DYRK3 | |
| SCHEMBL16013593 | 0.74 | CLK4 (0.52) | CCNCCDK8CCR1PLK4DYRK3 | |
| SCHEMBL16013538 | 0.73 | POLB (0.54) | CCNCCDK8CCR1PLK4DYRK3 | |
| SCHEMBL16014048 | 0.73 | CCR1 (0.50) | CCNCCDK8CCR1PLK4DYRK3 | |
| SCHEMBL15483262 | 0.73 | CCNC (0.52) | CCNCCDK8CCR1PLK4DYRK3 | |
| SCHEMBL8541628 | 0.73 | FERMT2 (0.57) | CCNCCDK8CCR1PLK4DYRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446604-A2 | Pyridine and related aza heterocycle derivatives as cardiovascular agents | AMERICAN CYANAMID COMPANY (US) | 1991-09-18 | — | — | EP | disclosed |