Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.55 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.55 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28623269 | 0.76 | CYP19A1 (0.55) | CYP19A1TBXAS1 | |
| SCHEMBL28538881 | 0.76 | CYP19A1 (0.51) | CYP19A1TBXAS1 | |
| SCHEMBL9849439 | 0.75 | CYP19A1 (0.48) | CYP19A1TBXAS1KMT2A | |
| SCHEMBL9849511 | 0.74 | TLR8 (0.57) | CYP19A1TBXAS1 | |
| SCHEMBL9849395 | 0.74 | CYP19A1 (0.52) | CYP19A1TBXAS1 | |
| SCHEMBL14829642 | 0.74 | CYP3A4 (0.55) | CYP19A1TBXAS1 | |
| SCHEMBL18940340 | 0.73 | CYP19A1 (0.49) | CYP19A1TBXAS1CYP11B1CYP11B2HMOX1 | |
| SCHEMBL11247886 | 0.73 | POLB (0.68) | CYP19A1TBXAS1KMT2A | |
| Hydrochloric Acid SCHEMBL22283559 | 0.72 | CYP19A1 (0.48) | CYP19A1TBXAS1CYP11B1CYP11B2MEN1 | |
| SCHEMBL15179017 | 0.72 | CYP19A1 (0.64) | CYP19A1TBXAS1CYP11B1CYP11B2HMOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446604-A2 | Pyridine and related aza heterocycle derivatives as cardiovascular agents | AMERICAN CYANAMID COMPANY (US) | 1991-09-18 | — | — | EP | disclosed |