Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9641548 | 0.78 | GAA (0.30) | GAAMAPTALOX15 | |
| SCHEMBL9641528 | 0.76 | GAA (0.35) | GAAMAPTALOX15ALDH1A1KDM4E | |
| SCHEMBL9641552 | 0.73 | GAA (0.32) | GAAMAPTALOX15ALDH1A1KDM4E | |
| SCHEMBL4683602 | 0.72 | PLK1 (0.42) | MAPTALOX15ALDH1A1HTT | |
| SCHEMBL9643026 | 0.66 | — | — | |
| SCHEMBL9641542 | 0.65 | GRM1 (0.37) | — | |
| SCHEMBL9641242 | 0.64 | KDM4E (0.33) | GAAMAPTKDM4EMAPK1HTT | |
| SCHEMBL9850007 | 0.63 | NPY2R (0.30) | — | |
| SCHEMBL9641249 | 0.63 | MEN1 (0.36) | ALDH1A1KDM4EKMT2AMEN1HTT | |
| SCHEMBL9195139 | 0.61 | MEN1 (0.51) | MAPTALOX15ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0427031-A2 | N-aryl-nitrogen heterocycles | BAYER AG (DE) | 1991-05-15 | — | — | EP | disclosed |