Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 18/20 | 1.00 |
| ▸ | CCNB1 | P14635 | 18/20 | 1.00 |
| ▸ | CDK2 | P24941 | 16/20 | 1.00 |
| ▸ | CCNA2 | P20248 | 15/20 | 1.00 |
| ▸ | CCNA1 | P78396 | 15/20 | 1.00 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.62 |
| ▸ | MGMT | P16455 | 5/20 | 0.56 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.55 |
| ▸ | CDK7 | P50613 | 1/20 | 0.55 |
| ▸ | CDK9 | P50750 | 1/20 | 0.55 |
| ▸ | CCNH | P51946 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682498 | 0.85 | CDK1 (1.00) | CDK1CCNB1CDK2CCNA2CCNA1 | |
| SCHEMBL7807591 | 0.82 | CDK1 (0.78) | CDK1CCNB1CDK2CCNA2CCNA1 | |
| SCHEMBL8618498 | 0.80 | CDK1 (0.77) | CDK1CCNB1CDK2CCNA2CCNA1 | |
| SCHEMBL30176198 | 0.80 | CDK1 (0.77) | CDK1CCNB1CDK2CCNA2CCNA1 | |
| SCHEMBL10338837 | 0.78 | CDK2 (0.63) | CDK1CCNB1CDK2CCNA2CCNA1 | |
| SCHEMBL8971208 | 0.78 | CDK1 (1.00) | CDK1CCNB1CDK2CCNA2CCNA1 | |
| SCHEMBL9850458 | 0.77 | CDK1 (0.63) | CDK1CCNB1CDK2CCNA2CCNA1 | |
| SCHEMBL7985300 | 0.77 | CDK1 (1.00) | CDK1CCNB1CDK2CCNA2CCNA1 | |
| Methylguanine SCHEMBL231097 | 0.77 | CDK1 (0.69) | CDK1CCNB1CDK2CCNA2CCNA1 | |
| Methylguanine SCHEMBL29903462 | 0.77 | CDK1 (0.69) | CDK1CCNB1CDK2CCNA2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421819-A1 | Therapeutic nucleosides | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-04-10 | — | — | EP | disclosed |