Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850739 | 1.00 | CYP3A4 (0.51) | CYP3A4CYP2D6TSHRRAB9AKDM4E | |
| SCHEMBL12173063 | 1.00 | CYP3A4 (0.51) | CYP3A4CYP2D6TSHRRAB9AKDM4E | |
| SCHEMBL3334395 | 0.93 | KDM4E (0.53) | CYP3A4CYP2D6TSHRRAB9AKDM4E | |
| SCHEMBL23634034 | 0.91 | KDM4E (0.47) | CYP3A4CYP2D6TSHRRAB9AKDM4E | |
| SCHEMBL29837257 | 0.89 | KDM4E (0.48) | CYP3A4CYP2D6RAB9AKDM4ENPC1 | |
| SCHEMBL31237102 | 0.87 | KDM4E (0.50) | CYP3A4CYP2D6TSHRRAB9AKDM4E | |
| SCHEMBL16322624 | 0.87 | KDM4E (0.50) | CYP3A4CYP2D6TSHRRAB9AKDM4E | |
| SCHEMBL29837259 | 0.85 | KDM4E (0.48) | CYP3A4CYP2D6RAB9AKDM4ENPC1 | |
| SCHEMBL23634035 | 0.82 | KDM4E (0.50) | RAB9AKDM4ENPC1MAPTALDH1A1 | |
| SCHEMBL29837272 | 0.82 | KDM4E (0.50) | RAB9AKDM4ENPC1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409634-A2 | Liquid crystal compounds and optically active compounds | SANYO CHEMICAL INDUSTRIES LTD. (JP) | 1991-01-23 | — | — | EP | disclosed |