Dimethylamine

Dimethylamine

SCHEMBL9851161

CCCCc1nc2cccc(CC)c2n1Cc1ccc(-c2ccccc2C#N)cc1.CNC

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.61
AGTR2 P50052 2/20 0.49
AGTR1 P30556 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9192065 0.91 PPARG (0.63) PPARGAGTR2AGTR1
SCHEMBL9194185 0.91 PPARG (0.63) PPARGAGTR2AGTR1
SCHEMBL9192150 0.91 PPARG (0.63) PPARGAGTR2AGTR1
Dimethylamine SCHEMBL9192520 0.90 PPARG (0.62) PPARGAGTR2AGTR1
SCHEMBL9198402 0.89 PPARG (0.61) PPARG
SCHEMBL9192512 0.88 PPARG (0.60) PPARGAGTR2AGTR1
SCHEMBL9851157 0.88 PPARG (0.59) PPARGAGTR2AGTR1
SCHEMBL9443254 0.87 PPARG (0.66) PPARGAGTR2AGTR1
SCHEMBL9195236 0.86 PPARG (0.64) PPARGAGTR2AGTR1
SCHEMBL9193729 0.84 PPARG (0.62) PPARGAGTR2AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0425921-A1 Benzimidazole derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1991-05-08 EP disclosed