Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RGS12 | O14924 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PRCP | P42785 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | TIPARP | Q7Z3E1 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9463190 | 1.00 | MAPT (0.49) | MAPTRGS12KDM4EMEN1CYP1A2 | |
| SCHEMBL9465105 | 0.81 | MAPT (0.35) | MAPTRGS12KDM4EMEN1CYP1A2 | |
| SCHEMBL9464110 | 0.80 | PRCP (0.37) | MAPTRGS12KDM4EMEN1CYP1A2 | |
| SCHEMBL11730138 | 0.79 | SLC6A2 (0.39) | MAPTRGS12KDM4EMEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL9463892 | 0.78 | PRCP (0.36) | MAPTRGS12KDM4EMEN1CYP1A2 | |
| SCHEMBL9462982 | 0.78 | SLC6A2 (0.39) | MAPTRGS12KDM4EMEN1CYP1A2 | |
| SCHEMBL9463514 | 0.78 | HTR2A (0.37) | MAPTRGS12KDM4EMEN1CYP1A2 | |
| SCHEMBL9463451 | 0.78 | HTR2C (0.36) | MAPTRGS12KDM4EMEN1CYP1A2 | |
| SCHEMBL9463417 | 0.78 | PRCP (0.50) | PRCPSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9463649 | 0.76 | PRCP (0.43) | PRCPSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413433-A1 | Isoindolyl-imidazole-derivatives and pharmaceutical compositions | Beecham Group p.l.c. (GB) | 1991-02-20 | — | — | EP | disclosed |