Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | EGFR | P00533 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9847997 | 1.00 | BLM (0.55) | BLMALDH1A1HSD17B10CYP3A4EGFR | |
| SCHEMBL13086896 | 0.83 | BLM (0.57) | BLMALDH1A1HSD17B10CYP3A4EGFR | |
| SCHEMBL13086903 | 0.83 | BLM (0.57) | BLMALDH1A1HSD17B10CYP3A4EGFR | |
| SCHEMBL12679277 | 0.83 | BLM (0.57) | BLMALDH1A1HSD17B10CYP3A4EGFR | |
| SCHEMBL6716593 | 0.83 | BLM (0.60) | BLMALDH1A1HSD17B10CYP3A4EGFR | |
| SCHEMBL6714798 | 0.83 | BLM (0.60) | BLMALDH1A1HSD17B10CYP3A4EGFR | |
| SCHEMBL6716600 | 0.83 | BLM (0.60) | BLMALDH1A1HSD17B10CYP3A4EGFR | |
| SCHEMBL6714802 | 0.83 | BLM (0.60) | BLMALDH1A1HSD17B10CYP3A4EGFR | |
| SCHEMBL22074721 | 0.81 | BLM (0.58) | BLMALDH1A1HSD17B10CYP3A4EGFR | |
| SCHEMBL9847966 | 0.81 | BLM (0.54) | BLMALDH1A1HSD17B10CYP3A4EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451422-A1 | Pharmaceutically active fluoromethyltyrosine compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-10-16 | — | — | EP | claimed |