Piperidine

Piperidine

SCHEMBL9851948

C1CCNCC1.O=C1CCCN1

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 1/20 0.75
CRBN Q96SW2 4/20 0.71
FKBP5 Q13451 1/20 0.71
KDM4E B2RXH2 2/20 0.48
GAA P10253 2/20 0.48
POLB P06746 1/20 0.48
ALDH1A1 P00352 1/20 0.45
CXCR4 P61073 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MERTK Q12866 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21238907 1.00 OR51E2 (0.75) OR51E2CRBNFKBP5KDM4EGAA
SCHEMBL21238913 1.00 OR51E2 (0.75) OR51E2CRBNFKBP5KDM4EGAA
SCHEMBL21238909 1.00 OR51E2 (0.75) OR51E2CRBNFKBP5KDM4EGAA
Piperidine SCHEMBL3787575 0.98 OR51E2 (0.71) OR51E2CRBNFKBP5KDM4EGAA
SCHEMBL21238724 0.97 OR51E2 (0.79) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL10332255 0.97 OR51E2 (0.79) OR51E2CRBNFKBP5KDM4EGAA
SCHEMBL7316123 0.95 CRBN (0.80) OR51E2CRBNFKBP5KDM4EGAA
Piperidine SCHEMBL7976338 0.95 CRBN (0.80) OR51E2CRBNFKBP5KDM4EGAA
SCHEMBL21238836 0.95 CRBN (0.80) OR51E2CRBNFKBP5KDM4EGAA
SCHEMBL21238842 0.95 CRBN (0.80) OR51E2CRBNFKBP5KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109248323-A Acylated GLP-1 derivative 杭州先为达生物科技有限公司 2019-01-22 CN disclosed
EP-0417901-A2 Abrasion resistant ionomer film MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-03-20 EP disclosed