Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9852298 | 0.99 | CACNA1C (0.36) | CACNA1CKDM4ELMNAESR1PTGS1 | |
| SCHEMBL9852293 | 0.97 | CACNA1C (0.37) | CACNA1CKDM4ELMNAESR1PTGS1 | |
| SCHEMBL8865013 | 0.96 | CACNA1C (0.36) | CACNA1CKDM4ELMNAESR1PTGS1 | |
| SCHEMBL9852090 | 0.93 | CACNA1C (0.37) | CACNA1CKDM4ELMNAESR1PTGS1 | |
| SCHEMBL8865119 | 0.93 | CACNA1C (0.38) | CACNA1CKDM4ELMNAESR1PTGS1 | |
| SCHEMBL9852300 | 0.91 | CACNA1C (0.35) | CACNA1CKDM4ELMNAESR1PTGS1 | |
| SCHEMBL8865170 | 0.90 | CACNA1C (0.35) | CACNA1CKDM4ELMNAESR1PTGS1 | |
| SCHEMBL9852269 | 0.90 | CACNA1C (0.37) | CACNA1CKDM4ELMNAESR1PTGS1 | |
| SCHEMBL9852143 | 0.89 | CACNA1C (0.34) | CACNA1CKDM4ELMNAESR1PTGS1 | |
| SCHEMBL8865046 | 0.88 | CACNA1C (0.38) | CACNA1CKDM4ELMNAESR1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433759-A1 | 4-Substituted alkyl carbapenem antibiotics | Bristol-Myers Squibb Company (US) | 1991-06-26 | — | — | EP | claimed |
| EP-0433759-A1 | 4-Substituted alkyl carbapenem antibiotics | Bristol-Myers Squibb Company (US) | 1991-06-26 | — | — | EP | disclosed |