Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 20/20 | 0.71 |
| ▸ | PDE3A | Q14432 | 20/20 | 0.71 |
| ▸ | PDE2A | O00408 | 4/20 | 0.59 |
| ▸ | P2RY12 | Q9H244 | 8/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10657130 | 0.83 | PDE3B (1.00) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL9852398 | 0.80 | PDE3B (0.70) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL10657144 | 0.76 | PDE3B (1.00) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL7323900 | 0.75 | PDE3B (1.00) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL7334731 | 0.74 | PDE3B (1.00) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL10661338 | 0.74 | PDE3B (1.00) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL10657958 | 0.74 | PDE3B (1.00) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL9852356 | 0.73 | PDE3B (1.00) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL10654057 | 0.73 | PDE3B (1.00) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL7325045 | 0.73 | PDE3B (1.00) | PDE3BPDE3APDE2AP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0426180-A2 | Imidazo[4,5-b] quinolinyloxyalkanoic acid amides with enhanced water solubility | Bristol-Myers Squibb Company (US) | 1991-05-08 | — | — | EP | claimed |