SCHEMBL9852695

C=CCO[C@H]1O[C@H](CO[Si](C)(C)C(C)(C)C)[C@@H](O)[C@H](OC(=O)C(=O)[C@H](CCCCCCCCCCC)C(=O)CCCCCCCCCCCCC)[C@H]1NC(=O)C[C@H](CCCCCCCCCCC)OCc1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	TLR4	O00206	12/20	0.38

▸	SELP	P16109	6/20	0.36

▸	MCHR1	Q99705	2/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9852674	1.00	TLR4 (0.38)	TLR4SELPMCHR1
SCHEMBL9019296	0.88	TLR4 (0.49)	TLR4SELP
SCHEMBL9019203	0.88	TLR4 (0.49)	TLR4SELP
SCHEMBL9852722	0.82	TLR4 (0.46)	TLR4SELP
SCHEMBL9852689	0.82	TLR4 (0.46)	TLR4SELP
SCHEMBL9786193	0.81	TLR4 (0.49)	TLR4SELP
SCHEMBL9786197	0.81	TLR4 (0.49)	TLR4SELP
SCHEMBL7454562	0.80	TLR4 (0.51)	TLR4SELPMCHR1
SCHEMBL9019095	0.79	TLR4 (0.55)	TLR4SELP
SCHEMBL9019097	0.79	TLR4 (0.55)	TLR4SELP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0437016-A2	Lipid A analogues having immunoactivating and anti-tumour activity	Sankyo Company Limited (JP)	1991-07-17	—	—	EP	disclosed